top of page

Program of CLEPIC 2022

2:00 - 3:45 PM

2:00 - 2:30 PM

2:30 - 3:00 PM

3:00 - 3:30 PM

3:30 - 3:45 PM

Session 1: Epigenetic Mechanisms

  • Albert Jeltsch: Investigation of the specificity and mechanism of DNA modifying enzymes by Deep Enzymology approaches

  • Angel de Lera: ​Adventures and nightmares: total synthesis of nahuoic acid, a SAM-competitive inhibitor of SETD8

  • Henk Stunnenberg: Systemic inflammation impairs interferon type I signalling and myeloid lineage development

  • Katarzyna Łagosz-Ćwik: Identification of key DNA methylation-sensitive cellular processes in gingival fibroblasts using the DNMT inhibitor decitabine: implications for periodontitis pathogenesis

Chaired by: Marianne Rots and Maria Berdasco

Chaired by: Lucia Altucci and Angel de Lera

  • Claudia Theys: Elucidation of epigenetic interplay of PPAR-alpha and mitochondrial metabolic functions in non-alcoholic fatty liver disease

6:15 - 6:30 PM

6:30 - 9:00 PM

Poster session and welcome finger food
at the conference area (3rd Floor)

Sponsored talk in Sponsors Meetings Auditorium BGI

Day 1

10:00 AM - 1 PM

12:00 - 1:00 PM

1:00 - 2:00 PM

1:00 - 1:15 PM

1:15 - 2:00 PM

Conference Hall Rybacka 1, Szczecin



Light lunch offered (3rd Floor)


  • Welcome by the Organizers and Editors-in-Chief of Clinical Epigenetics and Epigenetics Communications: Marianne Rots and Lucia Altucci

  • Opening Keynote by Susan Clark: The Cancer Epigenome

3:45 - 4:15 PM

Coffee break (1st Floor)

4:15 - 6:30 PM

4:15 - 4:45 PM

4:45 - 5:15 PM

5:15 - 5:45 PM

5:45 - 6:15 PM

Session 2: Epigenetics of disease

  • Charlotte Ling: Epigenetic modifications impact type 2 diabetes and may be used for precision medicine

  • Paola Arimondo: DNA methylome combined with chromosome cluster-oriented analysis provides an early signature for cutaneous melanoma aggressiveness.

  • Harold Snieder: DNA Methylation in Prevalent and Incident Type 2 Diabetes

  • Moshe Szyf: Deconvoluting the functional role of DNA methylation using CRISPR-mediated steric hindrance; implications for epigenetic therapy and prospects for epi-gene therapy

9:00 - 10:45 AM

9:00 - 9:30 AM

9:30 - 10:00 AM

10:00 - 10:30 AM

Session 3: Epigenetic Biomarkers

  • Maria Berdasco: Some shorts stories to consider in epigenetic biomarker discovery

  • Bożena Kamińska: Mapping chromatin accessibility and active regulatory elements in human gliomas reveals pathological mechanisms, new targets and biomarkers

  • Tomasz K Wojdacz: Epigenetic biomarkers and causal methylation changes in blood cells during SARS-CoV-2 infection

Chaired by: Harold Snieder and Pamela Munster

Chaired by: Bożena Kamińska-Kaczmarek and Paola Arimondo

2:15 AM - 3:45 PM

2:15 - 2:45 PM

2:45 - 3:15 PM

3:15 - 3:45 PM

Session 5: Epigenomic approaches
across the tree of life

  • Ryszard Maleszkal: "Nothing in [Epigenetics] Makes Sense Except in the Light of Evolution”

  • Frank Johannes: Spontaneous epimutations in plants

  • Isabel Bäurle: Adaptation to environmental stress by a chromatin-based stress memory

Chaired by: Albert Jeltsch and Joost HA Martens

Chaired by: Henk Stunnenberg and Frank Johannes

  • Anne Bozack: Prenatal essential and non-essential metal mixtures and differentially methylated regions in cord blood: application of AclustsCCA, a novel mixture method for epigenome-wide studies

5:45 - 6:00 PM

  • Joanna Borkowska: 5hmC profile as epigenetic marker differentiating adipose tissue-derived mesenchymal stromal cells from dermal fibroblasts

10:30 - 10:45 AM

  • Federica Sarno: Integrated biological and chemical epigenetic-targeting platform to improve cancer therapy

1:00 - 1:15 PM

Chaired by: Tomasz Wojdacz

8:00 - 11:00 PM

Conference dinner
at Pomeranian Dukes' Castle in Szczecin

Day 2

Conference Hall Rybacka 1, Szczecin


10:45 - 11:15 AM

Coffee break (1st Floor)

11:15 AM - 1:15 PM

11:15 - 11:45 AM

11:45 - 12:15 PM

12:15 - 12:45 PM

12:45 - 1:00 PM

Session 4: Cancer Epigenetics

  • Carmen Jeronimo: Uncovering the role of the epigenetically-regulated miR-30a/c-5p in renal cancer: from biology to the biomarker potential

  • Monika Hegi: Leveraging epigenetic vulnerabilities in glioma, biomarkers and drugable targets

  • Pamela Munster: Epigenetic modulation of PARP inhibitors in patients with HRD mutations

  • Olga Taryma-Leśniak: Long-term treatment with bortezomib induces specific methylation changes in neuronal cells

1:15 - 2:15 PM

Lunch break (3rd Floor)

  • Sponsored talk  in Sponsors Meetings Auditorium
    1st floor: Illumina

  • Sponsored talk in Lecture Hall
    ground floor: MethylDetect ApS

3:45 - 4:15 PM

Coffee break (1st Floor)

4:15 - 6:00 PM

4:15 - 4:45 PM

4:45 - 5:15 PM

5:15 - 5:45 PM

Session 6: Computational analysis of epigenomes

  • Simon Heath: Computational and statistical analysis of whole genome and epigenome profiles from EM-Seq on liquid biopsies

  • Joost HA Martens: Cis-regulatory elements-based transcription factor prediction using 5’-end capped RNA

  • Andrew E Teschendorff: Tackling the cell-type heterogeneity challenge in epigenome studies

6:15 - 7:00 PM

Keynote speech by Stephan Beck: Connecting Dots for (Epi)Genomic Medicine

9:00 - 10:45 AM

9:00 - 9:30 AM

9:30 - 10:00 AM

10:00 - 10:30 AM

10:30 - 10:45 AM

Session 7: Development and Ageing

  • Alex Meissner: Mechanisms of epigenetic regulation in development and disease

  • Riccardo Marioni: Updating and improving epigenetic predictors of chronological and biological age

  • Wolfgang Wagner: DNA methylation changes in aging and senescence

  • Renata Jurkowska: High-resolution transcriptomic and epigenetic profiling across disease stages identifies novel regulators of COPD

Chaired by: Monika Puzianowska-Kuźnicka and Wolfgang Wagner

Chaired by: Renata Jurkowska

12:30 - 1:30 PM

Lunch or pick up lunch break (3rd Floor)

Day 3

Conference Hall Rybacka 1, Szczecin


10:45 - 11:15 AM

Coffee break (1st Floor)

11:15 - 12:00 PM

Closing Keynote by Wolf Reik: Epigenetic regulation in development and ageing

12:00 - 12:30 PM

Awards and closing ceremony

Keynote Speakers

The CLEPIC 2022 keynote speakers included

Susan Clark

Garvan Institute of Medical Research


Stephan Beck

University College London, UK


Wolf Reik

Institute, UK

Click the speaker's box to find out more about them

Confirmed Speakers

The CLEPIC 2022 speakers will also include

Albert Jeltsch

University of Stuttgart, Germany

Angel de Lera

Universidade de Vigo, Spain

Paola Arimondo

Institut Pasteur, France

Henk Stunnenberg

Radboud University, Netherlands

Charlotte Ling

Lund University, Sweden

Bożena Kamińska

Necki Institute, Poland

Pamela Munster

University of California San Francisco, USA

Harold Snieder

University of Groningen, Netherlands

Maria Berdasco

Josep Carreras Leukaemia Research Institute, Spain

Tomasz K Wojdacz

Pomeranian Medical University, Poland

Ryszard Maleszka

The Australian National University, Australia

Frank Johannes

Technical University of Munich, Germany

Alex Meissner

Max Planck Institute, Germany

Nick La Thangue

University of Oxford, UK

Monika Hegi

University of Lausanne, Switzerland

Moshe Szyf

McGill University, Canada

Wolfgang Wagner

Stem Cell Network NRW, Germany

Riccardo Marioni

University of Edinburgh, UK

Isabel Bäurle

University of Potsdam, Germany

Simon Heath

Centro Nacional de Análisis Genómico, Spain

Joost HA Martens

Radboud University,

Andrew E Teschendorff

Chinese Academy of Sciences, China

Patrons 2022

MEiN logo_edited.jpg

Grant Ministerstwa Edukacji i Nauki, Nazwa projektu: ”Clinical Epigenetics International Conference (CLEPIC)”

Patronat Honorowy_kolor_2.jpg
bottom of page